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Occasionally, a mutation allows the virus to take hold in another species.
The D222G mutation allows the virus to bind to receptors on cells lining the lungs, which are slightly different from those in the nose and throat.
Perhaps even more importantly, Nowak said, the two drugs used simultaneously must not overlap: If a single mutation allows the cancer to become resistant to both drugs, the treatment will fail just as the single-drug therapy does.
This mutation allows the tumor to escape the growth suppressive effects of TGFβ SMAD signaling.
This novel mutation allows the study of nBMP2 without compromising BMP2 function.
This mutation allows the rapid and highly specific inactivation of Cdk1 by the bulky ATP analogue 1NMPP1.
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The separation of the two interacting loops by the S228P mutation allowed the solvent molecules to penetrate in the hydrophobic core of CTD (Fig. 6F) and thereby might retard CTD dehydration during refolding.
Moreover, analysis of one family with the 9106C>T BRCA2 mutation allowed the identification of common haplotypes for both microsatellite and intragenic polymorphisms segregating with the mutation.
Consistently, our haplotype analysis carried out in six Italian families with the IVS16-2A>G BRCallowedthen allowedetectionectiof of a common haplotype shared by all mutation carriers.
In these two cases, knowledge that the fetuses had inherited the GCK mutation allowed the maternal hyperglycemia in pregnancy to remain untreated.
The proposed method is novel in jointly modeling the multilocus haplotype pattern caused by recombination and mutation, allowing the analysis of haplotype data in recombining regions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com