Sentence examples for mutation affecting an from inspiring English sources

In both genes, a single missense mutation affecting an amino acid residue localized in the catalytic region of the protein accounted for >90% of reported events and were shown to change the substrate specificity of these enzymes.

Similarly, a deleterious mutation affecting an α-helix important in the interaction of two proteins was compensated by several different mutations in or in the vicinity of the same α-helix.

It is important to ask: what happens to brain circuitry when a mutation affecting a process such as cell migration or synaptogenesis is mutated?

A random mutation affecting a trait is more likely to detract from its functionality than to maintain or enhance it.

A mutation affecting a deeply engrained part of development, for instance the patterning of the body axis in a mammal, will have many deleterious effects and cannot be selected.

The rs384285149 mutation is a missense mutation affecting a highly conserved domain of EIF5A2.

A third Rut-C30-specific mutation affecting a gene element is in the gene 121453 encoding a metallopeptidase.

They thus do not mimic sporadic tumours that arise from an initiating mutation affecting a single cell in an otherwise normal microenvironment.

We also analyzed the percentage of WASp+ B cells within a WAS patient with a revertant mutation affecting a common lymphoid progenitor.

Therefore, we tested whether a recessive mutation affecting a very small proportion of patients in a case control study can still be detected using HRRA.

The availability of a gene product can become altered by a mutation affecting a control signal for the expression of the particular gene.