Sentence examples for mutation accumulation lines from inspiring English sources
Compensatory mutation has also been shown to facilitate substantial fitness recovery in mutation accumulation lines and natural populations previously overwhelmed by accumulated deleterious mutations [41] [43].
However, recent sequencing studies of mutation accumulation lines in model organisms demonstrate that substitutions generally do not accumulate at rates that would indicate a transitional bias.
Recently, a strong mutational bias toward A and T generating mutations was observed in mutation accumulation lines of Caenorhabditis nematodes (Denver et al. 2012).
Analyzing whole genome sequences for 68 mutation accumulation lines derived from 12 parental genotypes, reveals examples of mutator-allele-associated base-substitution biases, clustered mutations, and locus-specific patterns of mutations.
Mutational variance (Vm) was estimated through microarray gene expression measures across four mutation accumulation lines for 3,873 ORFs in the yeast interaction set (Landry et al. 2007).
The completion of the sequences of two closely related species, Arabidopsis lyrata and Brassica rapa, is complemented by genomic comparisons among A. thaliana accessions and mutation accumulation lines.
Transposon display assays of mutation-accumulation lines showed evidence for putative somatic insertions for two DIRS retroelement families.
For example, Joseph and Hall (2004) found that about 5% of mutations in yeast mutation-accumulation lines were beneficial.
Mutation-accumulation lines were initiated in August 2004, from offspring originating from a single individual of D. pulex (Log50) originally collected from western Oregon.
I assume that μ ^ = 5.8 × 10-9 per generation, the estimated average rate for single nucleotide mutations from D. melanogaster mutation-accumulation lines [ 70].
In S. cerevisiae, mutation-accumulation lines have been used to estimate the rate of nucleotide substitution in nuclear and mt genomes (Lynch et al. 2008).
