Sentence examples for mutation able to from inspiring English sources

The study by Zhang et al. [ 5] is of great value because it indicates a possible beneficial effect on longevity by an mtDNA somatic mutation able to restore the mitochondrial replication machinery.

In parallel with these findings, the hypothesis was proposed for the fungi Candida albicans claiming aneuploidy as a form of large-scale mutation able to confer adaptive phenotypes under diverse stress conditions (Zacchi et al. 2010).

This variation is able to determine an amino-acid change at position 675 of the protein, in a domain which is not far from the catalytic tyrosine (amino acid 723) but in a linker region where no drug-induced mutation able to confer drug resistance has been identified (Ohashi et al, 1996; Takatani et al, 1997; Pommier et al, 1999; Tsurutani et al, 2002; Woo et al, 2002).

Second, by the end of the forward evolution, several new mutations able to increase paraoxonase activity emerged due to epistasis.

Additional mutations able to restore replicative fitness to similar levels in the wild type such as rtV173L and rtP177S were not found.

Characterization of different mutations able to suppress the growth defect of the triple mutant [ 14- 16] has enabled identification of the crucial function of PKA.

Mutations able to suppress the elevated calcium requirement of a halAΔ sltAΔ strain were selected on medium containing BAPTA but no added calcium after ultraviolet mutagenesis (Fig. 7A).

The assumption we must make here is that whatever uncharacterised additional mutations these cells may have acquired along their journey to malignancy, these did not include mutations able to confer resistance to apoptosis in the more mature osteocyte.

In all five patients for whom we have contralateral samples, the left-right cell division occurring in early embryonic development appears near the root of the tree, with few mutations able to distinguish between the contralateral and ipsilateral lineages.

The continued pressure of chemotherapy may induce or select genomic mutations, able to alter the cytokine cross-talking network between cell migration and apoptosis: this would result in an acquired drug resistance phenotype [ 8].

The reduction of Complex I activity characterizes the decline of metabolism during aging; this event originates a favorable ground for the oncogenic expression of somatic mutations able to stimulate nutrient uptake.