Sentence examples for mutating the key from inspiring English sources

Similar results are observed for mutating the key acidic patch residues Asp488 and 490 from Uba2 (Figure 2B, Figure S3).

We next tested the effect of mutating the key residues in the putative TBM in human SLX4 on its interaction with TRF2.

Fingers with different triplet specificity can be engineered by mutating the key amino acid residues hence enabling specificity in DNA recognition by ensuring a large number of combinatorial possibilities.

Guided by the results from the docking analysis, we mutated the key amino acids predicted as responsible for BPA's agonistic activity: Ser247, Phe288, Trp299, Tyr306, and Leu308.

We show that mutating the two key phosphorylated serines in dynamin 1 to either alanine or aspartate both rescue the major endocytic defect of the dynamin 1/3 KO however they both eliminate the activity-dependent acceleration of endocytosis kinetics.

Two family GH-18 chitinases mutated on the key catalytic amino acids were evaluated as "glycosynthases" for the coupling of oxazoline activated donor to chitin oligosaccharide (COs) acceptors obtained from microbial fermentation.

This bacterium is unable to cause disease, because it is mutated in the key virulence factor delivery machine, the type III secretion system.

The AvrA mutant C186A is a single amino acid residue transition which is mutated at the key cysteine required for AvrA activity as previously described [14], [17].

The AvrA mutant C186A is a single amino acid residue transition which is mutated at the key cysteine required for AvrA's activity as previously described [14], [17].

DOI: http://dx.doi.org/10.7554/eLife.06866.008 We mutated either the key prolines or basic residues in the PR1 and PR2 regions proposed to bind p85α SH3.

Since the effect of mutating the S46 site is exacerbated in the absence of crh, it is feasible that CCR is key for exiting dormancy.