Sentence examples for mutating the acceptor from inspiring English sources

Identifying and mutating the acceptor lysine residues is one of the commonly used approaches for blocking sumoylation.

This is in agreement with a recent study [ 22] in which it was shown that mutating the acceptor site to a stronger site was more effective for full intron splicing of an alternative intron, than strengthening the donor site.

The effect of knocking down Ubc9 on the p63 concentration and activity was less than the effect of mutating the SUMO acceptor site.

Mutating the nonconserved residue 232 (Lys or Ala) at acceptor subsite +2 slightly altered CD ratios but also lowered CD yields (Nakagawa et al. 2006; Kelly et al. 2008a).

That furthered my sense of mutating the genres.

Residues F172 and D174 were mutated to disrupt the acceptor site for the tyrosine, whereas V392 and L395 were mutated to disrupt the acceptor site for the Y+3 residue, even though the Y+3 residue in the YSQA MHC-I CD sequence was not expected to bind this hydrophobic pocket.

Rather than mutate the description, semantic mutation testing mutates the semantics of the language in which the description is written.

Engineering CD specificity by mutating conserved acceptor subsites residues of CGTases is not advisable as this typically results in highly hydrolytic CGTases (Table  2) that form small quantities of CDs (Shim et al. 2004; Kelly et al. 2007).

To fully confirm the critical role for Drp1 SUMO-2/3-ylation in cytochrome c release, we made a non-SUMOylatable Drp1 by mutating four acceptor lysines to arginines (Drp1 4KR; Supplementary Figure 5C; Figueroa-Romero et al, 2009) and used this in knockdown rescue experiments.

The individuals may mutate the same genes according to mutation probability P m.

For the T2/GT2/tTA vector, an insertion into a gene in the opposite orientation is not predicted to mutate the gene, however, the T2/GT3/tTA would interrupt splicing with the HPRT splice acceptor, but will not express tTA.