Sentence examples for mutating it to from inspiring English sources

Deletion of the N-terminal threonine or mutating it to alanine led to inactivation of the proteasome [ 10].

Ala is also crucial for this, since mutating it to a proline residue abolishes activity against eEF2.

This lysine at position 481 is crucial for the polymerase function of PB1 in vivo but mutating it to alanine was tolerated in vitro [ 47].

Inactivation of this motif by mutating it to AAAA weakened the binding of neuronal Dab1 (Supplementary information, Figure S2B), indicating that this motif is involved in the interaction of EphB2 with Dab1.

Glu is also universally conserved, but mutating it to alanine, to eliminate the negative charge, actually enhanced activity against eEF2 and, strikingly, also increased phosphorylation of the MH-1 peptide.

To test if the equivalent cysteine in HOIP, Cys885, might also be forming the thioester, we mutated it to alanine and tested its catalytic activity.

Dr. Wimmer and colleagues took a part of the virus's RNA that is crucial for growth, mutated it to weaken it, and inserted it in another stretch of RNA that controls how virulent the virus is.

Post a liberal meme saying no one should die for lack of healthcare, and conservatives will mutate it to say no one should die because Obamacare rations their healthcare.

In order to further study the role of this arginine residue, we mutated it to the homologous lysine, which though differs in structure, can possibly provide the charge stabilization afforded by the arginine residue at this position.

To confirm the binding site and that the conserved tryptophan is essential in recognizing H3K4me3, we mutated it to alanine and probed the interaction by NMR.

To test our hypothesis that E364 is essential for the enzymatic activities of AgPPO8 by deprotonating phenolic substrates, we mutated it to a neutral Gln residue.