Sentence examples for mutated within the from inspiring English sources

The genes were mutated within the expected range of frequencies.

Furthermore, VirB8a has two critical residues mutated within the highly conserved "NPxG" motif (XPxX across the 13 Rickettsia genomes), which is not expected to adopt its critical sharp turn confirmation between helix α4 and strand β4 if altered [95].

Furthermore, mutagenesis and functional studies of PP1c mutated within the binding sequence of this motif will be used to determine the functional role of the FxxR/KxR/K-PP1c interaction on PP1 activity and on AIF mediated apoptosis.

To this aim, the enrichment was calculated by subtraction of controls ΔCt (unrelated REP protein (IP-REP) or TBPHF/L150-152 (IP-FL), a variant of TBPH mutated within the RNA binding domain control) from ΔCt of experimental sample overexpressing TBPH-wt (IP-GOF).

Likewise, immunoprecipitation experiments were performed using cells extracts from wild type W1118 flies as well as from flies overexpressing the unrelated Flag-tagged Drosophila protein REEP (Figure 6A, REP) or from flies overexpressing TBPH F/L150 152 (FL), a variant of TBPH mutated within the RNA binding domain (Figure 6A, FL, and see below).

HIPK2 was found downmodulated in thyroid, breast [19] and colon cancers [20] in comparison to the respective normal tissues; mutated within the speckle retention signal in human acute myeloblastic leukemias and in myelodysplastic syndrome [21]; and delocalized in the cytoplasm by high-mobility group A1 (HMGA1) overexpression [22].

When the Luc- BRCA1 3′UTR vector was mutated within this target site, miR-146a- or miR-146b-5p-mediated miR-146b-5p-mediated miR-146b-5p-mediated miR-146b-5p-mediateds (Fig 1C), suggesting specificity of the repression effect.

Altered magnesium optima were seen in proteins mutated within these motifs in human topoisomerase IIβ and two possible binding sites were proposed for the metal ion(s) needed for DNA cleavage [18].

Shapes and textures kept mutating within the din.

Themes and forms would mutate within the developing context, but the processes making the literature of early modern France are characterized by struggle rather than by any clear moment of change.

Since the P-loop of AtEHD2 is 100% conserved with the human EHD P-loop, we chose to mutate (within the P-loop) the Glycine that generated a dominant negative mutant in human EHDs, to Argenine [38], thereby generating AtEHD2_G221R.