Sentence examples for mutated to their from inspiring English sources

In each variant, two or a few residues were mutated to their mkNTCP counterparts.

However, even when both these residues are mutated to their counterparts in MCT4, significant inhibition is observed at 10 μM which is not the case for MCT4.

When the 7 nucleotides in this region were mutated to their Watson-Crick (W-C) complement the RNA remained essentially fully resistant to Xrn1.

Let p j ∗ for 1 ≤ j ≤ 5 be defined as follows: at time t, if j positions have been mutated to their WT residue, p j ∗ is the probability that no other positions will be mutated to their WT residue at the next time step.

The amino acids surrounding the inhibitor in this docked position were mutated to their equivalent in MCT4 (as determined by sequence alignment) or, if the same in MCT4, to alanine and the modified MCT1 constructs expressed in oocytes for measurement of AR-C155858 inhibition of L-lactate transport.

Current knowledge does not allow the prediction of when low pathogenic avian influenza virus (LPAIV) of the H5 and H7 subtypes infecting poultry will mutate to their highly pathogenic phenotype (HPAIV).

The catalytic (H12 and H47) and metal-ion binding (E32 and D34) residues in Loxosceles intermedia phospholipase D (LiRecDT1) were mutated to understand their roles in the observed activities.

In this study, the corresponding residues of HpyAV (His294, His295, Asn311 and His320) were mutated to verify their role in catalysis.

Predicted TF binding sites on human promoters from ChIP-seq data in conjunction with position weight matrix (PWM) searches of known motifs were mutated to assess their function using luciferase reporter assays in four different immortalized human cell lines.

In this study, the residues in the lyase domain of VenL that are conserved in the active site of OspF proteins were mutated to evaluate their importance for catalysis.

In Kafka-esque style, they mutated to three times their English farmyard size, grew savage tusks and now eviscerate the earth, overturning trees and destroying habitat.