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To inactivate the GL domain, the amino acid residue E1128 was mutated to an alanine (E1128A mutation).
The Kras gene is mutated to an oncogenic form in most pancreatic tumors.
The amber stop codon suppression is commonly employed, in which the target-location codon is mutated to an amber stop codon [219].
The 50th codon in IP107 (CAG) is mutated to an amber nonsense codon and the respective protein stops after Gln49.
When W216 was mutated to an arginine, Endo-A lost its ability to carry out transglycosylation [24].
Each targeted cysteine was mutated to an alanine residue, which cannot co-ordinate an [Fe-S] centre.
Similar(10)
In the set of the evolutionarily conserved mutations, we isolated the P1 mutant, in which a conserved tyrosine residue is mutated to a histidine residue.
But in nine months it mutated to a highly virulent one.
Therefore, a CG base pair will have mutated to a TA base pair.
On protecting America against terrorists, their nine-point advantage has mutated to a seven-point deficit.
Initially it caused only mild disease that escaped detection, but by 1997 the virus had mutated to a deadly form that could kill chickens within 48 hours.
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