Sentence examples for mutated the same from inspiring English sources

Having mutated the same residue as in this yeast clathrin heavy chain mutant we expected an altered clathrin staining pattern within the cells.

When Lavista-Llanos et al. mutated the same gene in another Drosophila species, the mutant flies produced fewer eggs and abnormally accumulated an enzyme (which makes l-DOPA) inside their developing eggs—just like Drosophila sechellia.

We mutated the same residues as those shown in ScRAD5 to disrupt the highly conserved ATP-binding site of the SNF2-related helicase domain and the E3 ubiquitin ligase domain.

The individuals may mutate the same genes according to mutation probability P m.

Using a kernel width of 5 kb, we found that insertions in frequently mutated genes like Flt3, Notch1, Jundm2 and Ikaros are unevenly distributed into clusters that may mutate the same genes by different mechanisms.

We also performed a more stringent test in which we compared the observed PWM score changes with those that result from randomly mutating the same position in the TFBS.

It would have enhanced the study to know which factors bind to this region, or data on the phenotypic consequences of engineering a correction of this change, or of mutating the same base, but to a different substitution.

Recurring mutations are more likely to be population-specific polymorphisms, and thus not captured by aspecific population databases, than de novo variation, which is believed to randomly occur throughout the genome and therefore has a very low probability of mutating the same position four times in non-consanguineous individuals.

However, very few methods involve a principled procedure for taking account of pathway interactions, i.e. pathways that are mutated in the same sample, and that are mutated together across a large subset of samples.

Thirty-nine of the 41 genes mutated either in our study or in the TCGA dataset were mutated in the same fraction of samples (P ≥0.05; Figure  3).

Oncogenes tend to be recurrently mutated at the same amino acid positions, whereas tumor suppressor genes are generally mutated in various positions throughout their length.