Sentence examples for mutated or unmutated from inspiring English sources

However, pathogenetic mechanisms of JAK2 mutated or unmutated Ph-MPN remain not completely understood.

Chronic lymphocytic leukemia (CLL) includes cases featuring somatically mutated or unmutated immunoglobulin heavy variable genes (IGVH).

Previous work suggested that CLL with mutated or unmutated IGHV are derived from memory and naive B cells, respectively.

Chronic lymphocytic leukemia (CLL) is unique among B cell malignancies in that the malignant clones can be featured either somatically mutated or unmutated IGVH genes.

The definition of mutated or unmutated CLL is based on an arbitrarily defined threshold of 98%% homology to the most similar germline gene.

DNA methylation arrays detect representative methylation sites across the entire genome and have been used to identify regions with differential methylation in CLL samples with mutated or unmutated IGHV status [ 95].

Patients are classified as either VH-mutated or unmutated (M/NM).

The CLL cases may be divided in two major groups regarding to mutated (M) or unmutated (UM) immunoglobulin heavy chain variable region gene (IGHV) where patients with an unmutated IGHV clone have a more adverse prognosis than patients with mutated IGHV gene [ 3, 4].

Because the IGVH mutational status is a good survival predictor, genes that are differentially expressed in mutated versus unmutated subtypes are also meaningful in prognosis.

Recent studies have demonstrated substantial differences in genomic alterations between mutated and unmutated IGHV subgroups, which reflect distinct molecular pathways and mutagenic mechanisms in the pathogenesis of the disease.

Numerous genes were suggested based on gene expression profiles comparing IgVH mutated and unmutated patients [7], [8].