Sentence examples for mutated it to from inspiring English sources

To test if the equivalent cysteine in HOIP, Cys885, might also be forming the thioester, we mutated it to alanine and tested its catalytic activity.

Dr. Wimmer and colleagues took a part of the virus's RNA that is crucial for growth, mutated it to weaken it, and inserted it in another stretch of RNA that controls how virulent the virus is.

In order to further study the role of this arginine residue, we mutated it to the homologous lysine, which though differs in structure, can possibly provide the charge stabilization afforded by the arginine residue at this position.

To test our hypothesis that E364 is essential for the enzymatic activities of AgPPO8 by deprotonating phenolic substrates, we mutated it to a neutral Gln residue.

To confirm the binding site and that the conserved tryptophan is essential in recognizing H3K4me3, we mutated it to alanine and probed the interaction by NMR.

Because these results suggested that the DARPP-32 cleavage site is likely to be near the C-terminal region, we selected Thr153 as a potential cleavage site and mutated it to alanine (DARPP-32 T153A).

Post a liberal meme saying no one should die for lack of healthcare, and conservatives will mutate it to say no one should die because Obamacare rations their healthcare.

Deletion of the N-terminal threonine or mutating it to alanine led to inactivation of the proteasome [ 10].

Ala is also crucial for this, since mutating it to a proline residue abolishes activity against eEF2.

This lysine at position 481 is crucial for the polymerase function of PB1 in vivo but mutating it to alanine was tolerated in vitro [ 47].

Glu is also universally conserved, but mutating it to alanine, to eliminate the negative charge, actually enhanced activity against eEF2 and, strikingly, also increased phosphorylation of the MH-1 peptide.