Sentence examples for mutated in three from inspiring English sources

Title Two critical positions in zinc finger domains are heavily mutated in three human cancer types.

Moreover, rpoBC encoding RNA polymerase subunits were mutated in three independent isolates of TR7 relative to HR23.

ASXL1 was mutated in three (50%) and six (29%) of the responding and non-responding patients, respectively (P=0.367).

For this data set, we chose the 2009 version of the FI network, and picked genes mutated in three or more samples to construct a FI sub-network.

For example, the enzymes responsible for the H3K4me1/me2 epigenetic modifications, specifically the MLL2, MLL3 and MLL4 genes, are significantly mutated in three or more cancer types [ 122, 127, 129].

The linker region implicated in E. coli CtpS polymerization is also mutated in three independent human lung carcinoma samples (Forbes et al., 2008), suggesting that metabolic regulation by CtpS polymerization is important for limiting human cell proliferation.

One of these peaks corresponds to the cortactin-binding protein-2 domain, CortBP2, that was mutated in four genes, CTTNBP2NL (1 mutation), CTTNBP2 (2 mutations), FILIP1 (5 mutations), and FILIP1L (1 mutation).

In contrast, the disease-causing nsSNPs tend to be concentrated at structurally equivalent positions, with a significant excess of mutations occurring at positions mutated in four or more different protein kinases.

ACE2 was mutated in eight evolved clones; six of these mutations were nonsense mutations scattered through the open reading frame.

Although not typically mutated in pancreatic cancer, Pten was highly mutated in two recent screens for gene mutations that accelerate KrasG12D-driven pancreatic tumorigenesis.

The gene is persistently mutated in eight series, (three of which were driver mutations), followed by ten genes mutated in seven series.