Sentence examples for mutated in some from inspiring English sources

It has been also suggested that mutations in α-synuclein, a protein mutated in some familial forms of PD, could result in a reduced number of vesicles being available for dopamine storage, leading to an accumulation of dopamine in the cytoplasm and increased levels of oxidative stress [30], [31].

The AKT1 gene, which is part of a cell-growth pathway, has also been found to be mutated in some cancers.

We suggest that MSH3 has different substrate specificities than the other mismatch repair proteins and that the human MSH3 homolog (MRP1) may be mutated in some tumors with microsatellite instability.

The group examined a section of DNA known to be mutated in some short people; the section lay in a so-called pseudoautosomal region (PAR) that is identical in the X and Y chromosomes.

Jans and colleagues modified the second NLS in SRY molecules in the same way that it is mutated in some sex-reversed people; the engineered protein failed to bind calmodulin.

The gene for this protein is mutated in some human patients with inflammatory bowel disease, and mice lacking the gene for NFIL3, the team found, had more so-called TH17 cells in their intestines.

This meant that the tests for Ebola could be updated quickly as the virus changed, and that the scientists might also be able to see it mutating in some dangerous direction.

Notably, Pten and PIK3CA are co-mutated in some human TNBCs (Yuan & Cantley, 2008; Lehmann et al, 2011), suggesting that mutations in more than one gene on the PI3K pathway may be required to fully activate the pathway, which is tightly autoregulated in normal cells (Cully et al, 2006).

In support of such a hypothesis, it has been reported that when mutated in the NBD, some ABC exporters function as PMF-driven transporters (Davidson et al., 2008).

A new study of golden retriever DNA shows that the same gene is mutated in the dogs and in some people, offering a much-needed clue to the disease's origins.

Although some studies have found CtIP/RBBP8 to be mutated in tumor samples [ 18– 21], and some general screenings using RT-polymerase chain reaction (PCR) have found changes in its mRNA levels (Oncomine), we describe here the first systematic study of the presence of CtIP/RBBP8 at the protein level.