Sentence examples for mutated in all from inspiring English sources

Mutations were generated such that each VDRE (containing two half-sites, each) was mutated in all seven possible combinations of single mutations, double mutations, and one triple mutation.

The gene IKBKAP, which encodes the IKAP/hELP1 (IKAP) protein, was found to be mutated in all FD patients; the mutation in 99% of the patients is a T→C nucleotide transition in the donor splice site of intron 20.

It approaches one when a gene is mutated in all tumour types with almost identical mutation frequency.

Moreover, ZNF664 mutation, (common in IR1 and ER1 samples) was also found mutated in all of the recurrence samples but not in the primary tumor.

The chromosomal position of called mutations were processed using YeastMine Genomic DNA Search function (Balakrishnan et al. 2012) to determine whether the mutations fell within genes and whether the same gene was mutated in all six isolates.

In contrast, the majority of mutations mapped are 'passenger' mutations in genes that do not significantly contribute to oncogenesis and are infrequently mutated in all cancers.

Almost all the miRNAs appear mutated in almost all the populations and the same can be said for the diseases.

A similar enrichment was identified in genes involved in histone modification (EED, EZH2 and SUZ12), which were more commonly mutated in ETP ALL (42%) compared with non-ETP ALL (12% P=0.0001).

Furthermore, genes involved in hematopoiesis and lymphoid development (RUNX1, IKZF1, ETV6, GATA3 and EP300) were also more frequently mutated in ETP ALL (58%) than that in non-ETP ALL (17% P<0.0001).

Of these mutations, Kras is found to be mutated in almost all cases (75 90%) of PC and represents an early event in the development and progression of this malignancy (Almoguera et al, 1988; Shibata et al, 1990; Caldas and Kern, 1995; Dergham et al, 1997; Moskaluk et al, 1997; Wang et al, 2002).

Transgenic constructs driving expression of Cre recombinase under the control of a combination of cell-specific promoters active in the various tissues of interest were introduced in mice carrying floxed alleles not only in Brca1, but also in p53, a gene mutated in almost all human cancers associated with the BRCA1 mutation carrier state (Ahmed et al., 2010).