Sentence examples for mutated for the from inspiring English sources
Amino acid residues mutated for the creation of D-amino acid.
The sequence alignment of meso- DAPDHs of U. thermosphaericus and other four bacterial strains indicates that all five amino acids (Q150, D154, T169, R195 and H244) in C. glutamicum enzyme mutated for the creation of D-amino acid dehydrogenase are perfectly conserved in the sequences of other bacterial enzymes containing U. thermosphaericus enzyme (Figure 1).
Because it is autosomal dominant, only one copy of the gene needs to be mutated for the individual to be affected by the disease.
The mutation that causes chorea acanthocytosis is passed in an autosomal recessive manner, meaning that both alleles of the gene must be mutated for the person to have the disease.
Although Fas expression has been related to p53 status by several authors [20], [21], these effects were independent of p53 since both cell lines were mutated for the protein.
To address this question we analyzed mice mutated for the NAD+ hydrolase CD38.
The Rad59 residues mutated for this study were Tyr92, Lys166, Lys174, and Phe180 (Fig. 2).
When such composition dynamics are at work, bacterial GC contents comply with our grouping scheme, regardless of whether they are mutating for the better or are being selected and suffering a bottleneck.
However, studies in mice mutated for Fto, the homolog of the human obesity susceptibility gene FTO, have demonstrated peripheral metabolic effects of this gene [ 17, 18].
Some of the conserved residues at subunit interfaces of thermophilic xylose isomerases (XIs) were selected by means of both multiple sequences alignment and subunit interactions analysis of XIs, and then were mutated for improving the activity of Thermus thermophilus xylose isomerase (TtXI).
In the present panel of seven head and neck cell lines, the high proportion of cell lines mutated for p53 concurs with the mutational status of p53 in oral carcinomas and supports the clinical relevance of the experimental model used in this study.
