Sentence examples for mutated compared to from inspiring English sources
On the target-1, only 2 mutants were identified from 96 independent lines using hSpCas9 (2.1% mutated), compared to the 15.6% mutagenesis frequency using pSpCas9 (Figure 1b).
The two pseudogenes NWDp1 and NWDp2 are heavily mutated compared to wild type NWD1 sequence.
Vemurafenib exhibits an approximately 30-fold selectivity for p.V600E mutated compared to wildtype BRAF melanomas.
In ZL55 cells serum starvation induced a five-fold increase of nuclei positive for Serine1981-phosphorylated AtaxiaTelangiectasiactasia Mutated), compared to untreated control.
Somatic hypermutation and isotype switch of Ig genes, which classically characterize T cell-dependent GC responses, can also occur extrafollicularly upon TLR signaling, and some RF clones from RA patients are indeed somatically mutated compared to healthy subjects [ 23].
Also, median OS was longer in patients harbouring aberrations, 30.9 months for IDH1/IDH2 mutated and 9.1 months for TP53 mutated, compared to 6.2 months for the group without mutations.
Finally, recent data from 27 mCRC patients observed only one responder out of 10 mutated tumors compared to 9 out of 17 non mutated tumors[ 17].
Loss of heterozygosity was performed by sequencing paired tumor/normal archival DNA samples and comparing sequence autoradiograms for a decrease in the intensity of the non-mutated signal compared to the mutated sequence (Table S2).
Although we studied only GBM cases, our results showed that IDH1/IDH2 mutations were more powerful prognostic factors than primary/secondary GBM classification; we observed better OS in primary GBM with mutated IDH1/IDH2 compared to the secondary GBM with no mutation).
Moreover, BRCA1 protein was significantly more expressed in BRCA1-mutated tumours compared to BRCA2-mutated tumours.
We first assessed if the TRMs_100 tended to contain a greater number of mutated genes compared to lower-ranked functional modules by calculating the ratio of their percentages of mutated genes.
