Sentence examples for mutated at a from inspiring English sources

iii) Mutation: The new created individual will be mutated at a definite point in the chromosome.  .

Among the genes harboring significant somatic variants, we found CDKN2A to be mutated only in the never-smokers and past smokers, PIK3CA to be mutated only in the smokers, and TP53 to be mutated at a 20% greater frequency in the smokers, CASP8 mutation has a 12% greater frequency in those that consumed alcohol or chewed tobacco.

Specifically, in addition to the standard model where a cancer gene is frequently mutated at a specific location in a gene such as the V600E mutation in BRAF (D avies et al. 2002), there is increasing evidence that there are many driving mutations in genes occurring at a very low prevalence (G reenman et al. 2007; C arter et al. 2009).

Here, site-directed mutagenesis created Elk-1 mRNA mutated at a single site.

The promoter was mutated at a single TCF4/Lef1 binding site or both binding sites at a time.

In order to map the RNF10-binding motif within the SSE sequence, we analyzed a series of oligonucleotides in which 2 bases were mutated at a time.

In microsatellite unstable tumours MBD4 can itself be mutated at an exonic polynucleotide tract.

Recently, the chromatin regulator genes CHD7 and CHD8 were found to be mutated at an enriched frequency in CIMP-positive colorectal cancers compared to CIMP-negative.

When we allowed all SNP markers to mutate at a mutation rate equal to 10-6, we found a loss of accuracy of about 20-25% for HaploMax and about 50% for HAPimLDL (data not shown).

For each artificial sequence, we mutate at a 50 mutation rate per length of the beta strands.

Thus, the largest difference between the population genetic enviroments of the piRNA and CRISPR systems is the mutation rate since the phage can mutate at a much faster rate and evade CRISPR-mediated repression than transposable elements can evade piRNA-mediated repression.