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In the case of one of the miR-148 binding site, 148/152A, only 4 bases were mutated as a clone with the fully mutated binding site was not generated successfully.
Other codons in LRRK2 are also frequently mutated as a consequence of numerous independent mutational events.
Unknown to the girls, Mojo Jojo was Professor Utonium's lab chimp helper who was mutated as a cause from the Powerpuff Girls being made and has become super smart as a result and jealous of them.
In Keller, some of the motifs have been mutated; as a result, no expression was detected.
DHCR24 up-regulation in HCV infection may be due to increased Sp1 phosphorylation by ataxia telangiectasia mutated as a result of HCV-induced oxidative stress, which promotes transcriptional activation of DHCR24 (Tsukiyama-Kohara, 2012).
It is often claimed that normal mutation rates are too low to account for changes in the five or six genes generally supposed to be mutated, as a minimum, for a cancer to occur [ 7].
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Future studies to explore these targets could consider analyses using gene-specific 3-UTR luciferase constructs in which putative miRNA binding sites have been mutated, as well as an evaluation of their effects in the specific target cells of interest, such as hepatoblasts.
11 p.m. 9) NEO-WEIMAR Few streets have mutated as much as Oranienburger Strasse, the spine of Mitte.
Scientists say the mutation problems and complexity might be overcome if targeted drugs are used early, when the tumor cells have not mutated as much.
But the human immunodeficiency virus, which causes AIDS, mutates as much in a single day as flu virus does in a year, presenting scientists with an almost insurmountable challenge.
He attacks Sterns, who gets some of Banner's blood in a cut on his forehead, causing him to begin mutating as well.
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