Sentence examples for mutants with very from inspiring English sources
This correlation was confirmed by systematically engineering IFNα2 mutants with very high differential antiproliferative potency.
And while there is certainly a very popular place for men in capes, or dressed as animals, or part men/part animal hero mutants with very large guns, there is also a place, perhaps smaller, for something a little more challenging.
We identified two novel remote memory mutants with very diverse cellular roles, Itgβ2−/− and Soat1−/−.
When the effect of mutation goes beyond the range given by the phenotypic noise, mutants with very low fitness values begin to accumulate.
Indeed, there may appear mutants with very low fitness values from an individual with a high fitness value, only by a single change of a path in the network.
This mechanism increases the effective activity of IFN mutants with very low efficiency as monomers (K133A and R144A).
Substitution of Asp for Asn yielded an acidic ChiB mutant, with very low activity at pH 7, but significant (wild-type like) activity at pH 4.5 [ 9].
The nfyb-1 (cu13 ); tbx-2 (bx59 ) double mutant expressed Ptbx-2:: gfp in a pattern that was very similar to the nfyb-1 (cu13 ) single mutant, with very strong expression in the head neurons and frequent expression in the gut.
We expected that a double mutant containing both a disrupted proximal site and deleted distal sites (Ptbx-2 prox+dist) would exhibit an additive expression pattern, but Ptbx-2 prox+dist was expressed in a pattern very similar to the Ptbx-2:: gfp dist single mutant, with very frequent expression in the gut but very little expression in the seam cells (Table 1).
The cuticles from shgR64 mutant embryos expressing Rab11DN in the engrailed domain also exhibit a stronger phenotype than shgR64 mutant embryos, with very big dorsal holes and lateral holes (Figure S2L).
In addition we noted that Atoh8 mRNA was strongly down-regulated in liver expression microarrays of Tfrhpx/hpx mice (Patel et al, 2012), a mutant with a very high degree of liver iron overload, chronic anaemia and very low Hamp1 levels.
