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The cover of Mrs. Stouffer's book "The Legend of Rah and the Muggles" previously depicted her miniature mutants, with the word "muggles" in small print.
We designed and produced a number of mutants with the aim to increase its thermostability.
We designed and created two loop mutants with the aim to increase their overall stability.
Therefore, the gene expression results agree with the binding affinities of PHD1KDM5B and its mutants with the H3 peptide.
Less than 5% of the ALK inhibitors bind potently to EGFR and its mutants, with the notable exception of the double mutant EGFR- L858R, T790M).
We next fused m36 and its mutants with the first two domains (soluble CD4, sCD4) of the human CD4 using a polypeptide linker.
The function of these proteins will be examined using mutants with the goal of identifying the ROS signaling network that defines root architecture.
In this review we analyze the characteristics of GR mutants with the aim of assisting the design and interpretation of GR mutant-based experiments.
Combinations of these mutations with others that lead to a reverse phenotype or altered inducer specificity yielded new TetR mutants with the respective combined activities.
Further, crystal structures of the two mutants with the worst packing, as measured by interaction energies, showed no unusual disorder in the core.
These results could guide the selection of env mutants with the fewest antigenic and functional alterations but with enhanced neutralization sensitivity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com