Sentence examples for mutants with small from inspiring English sources
The uricase of Bacillus fastidious is a promising biodrug for treating refractory gout and a suitable tool for serum uric acid assay [32 34]; we cloned this uricase gene and obtained some mutants with small differences in catalytic capacities.
SV40 mutants with small deletions or base substitutions have been isolated by in vitro site-specific or random local mutagenesis of recombinant DNA followed by cloning in E. coli.
The log-fold change distributions of known miRNA targets were also very similar between mutants with large transcriptome changes and mutants with small transcriptome changes (Figure S2).
Surprisingly, however, many mutants with small birth size did not have a small size overall (ρ = 0.40; see Figure 3).
Many mutants with small birth size also had normal %G1 DNA content (see Figure 5, and File S1).
The general conclusion from the behavior of this system is that populations can respond rapidly to selection, when mutants with small improvements are common.
The high mutational heritability could be due to a few mutants of large effect, or many mutants with smaller effects.
The reduction in chromocenter number in crwn1 crwn2 mutants, as well as crwn4 mutants with smaller nuclei, is consistent with aggregation of individual chromocenters.
It has been found that mutants with smaller trichomes contain less DNA, whereas mutants with increased cell size were found to have additional endoreduplication rounds [ 46].
At a genome-wide scale, similar deletion profiles to the larger deletions (523 bp and ~5 kb) were observed for other Arabidopsis mutants with smaller deletions (4 bp, 28 bp and 104 bp).
The reduction in chromocenter number in crwn1 crwn2 and crwn4 mutants with smaller nuclei could reflect the aggregation of individual chromocenters in the limited confines of these nuclei, but a similar clustering does not occur in small wild-type nuclei, arguing that small nuclear dimensions alone are insufficient to cause clustering.
