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On the other hand, Vos et al. showed that in certain yeast mutants with no apparent growth defect, production of functional small ribosomal subunits completely depends on a rRNA processing pathway which involves 21S rRNA as an intermediate [31].
This LacZ staining is much reduced in runt mutants, with no discernible gradient, as in wg mutants.
Mutants could be divided into three different groups: HL sensitive mutants, t-BOOH resistant mutants and mutants with no or only minor changes in tolerance (not shown).
The second consisted of 657 mutants having an effect on protein stability and 652 mutants with no effect on stability covered by 47 proteins [ 19, 20].
Although inflammation was observed for both genotypes, goblet cell metaplasia was solely seen in mutants with no effect on FOXA2 expression (supplementary material Fig. S1A E).
Of the 17 mutants with no obvious growth impairment at 25°, 11 displayed a noticeable growth defect when animals were shifted to 30°.
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The first NAC gene to be characterized was NAM, which was discovered in a seedling-lethal mutant with no SAM in Petunia (Souer et al., 1996).
In the sor1 mutant, with no or little fusion protein, 26SP function is expected to be restored back to the wild-type level.
An amp1 mutant was found to be deficient in stimulating miRNA activity, and intriguingly, miRNA target protein levels were elevated in this mutant with no corresponding changes in target mRNA levels.
We got hold of a zebrafish mutant with no blood from Walter Gilbert's lab and, within a week, people were saying to me: "you're going to be a zebrafish researcher".
The second PCR product obtained using 0.05 pmole of the first flanking primer showed only the bands corresponding to the anticipated mutant with no band of undigested (wild-type) product.
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