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The bacterial mutants with good oxidation activity on Fe2+ were selected in gold concentrates bioleaching experiments.
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Several types of mutant GFP with good stability and enhanced fluorescent brightness have already been commercialized.
Incidental and strain-associated background lesions were present in all mutant lines with good concordance to wild-type controls.
Interestingly, mutant G268A also exhibits a significant decrease in affinity, suggesting that it may be peripherally involved in binding, and mutant V264A binds sugar with good affinity, demonstrating that it is not a component of the sugar-binding site.
We identify several duplex RNAs and ss-siRNAs that target CAG repeats and inhibit expression of mutant ATN-1 protein with good selectivity relative to the selectivity of inhibition of wild-type protein expression.
The complementation of the lrx3 lrx4 double mutant with LRX3 and LRX4 combined with the analysis of the double/triple mutants provide good evidence that the mutant phenotypes observed are indeed caused by the mutations in these three LRX genes.
Development of mutants and genetic engineering studies is an emerging area with good prospects in enzyme development with desired properties.
Switching to Tris-HCl-buffered gels produced sharper bands with good separation of wild-type and mutant protein.
Therefore, in a near-isogenic state with a wild-type (WT), these mutants represent good model system to study fiber elongation.
In the case with good drug effect, drug effector pathways are abnormally activated, which could be caused by two different mutant oncogenes in this pathway.
These properties make S. elongatus PCC 7942 a good model strain to isolate mutants with an enhanced fatty acid production.
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