Sentence examples for mutants with distinct from inspiring English sources
The disrupted ORF was identified for each potential attenuated mutant, and mutants with distinct and unique mutated ORFs were analyzed individually for attenuation in mouse and CDCD pig models.
We also studied in combination CM mutants with distinct activating and deactivating properties.
The schematic representations of the three SOCS3 mutants with distinct functional domains deleted were shown in Fig. 1.
By means of auxanographic assays, for 63% of the 295 isolated auxotrophic mutants with distinct phenotypes various nutritional requirements could be identified.
Indeed, we observe disrupted BMP target gene expression in mew and scb single mutants, with distinct spatial pattern of Race defects.
In a separate study, the fatty acid contents of two in vitro-selected RIFR Mtb mutants with distinct rpoB mutations (S531L and S522L) were analyzed by gas chromatography mass spectrometry.
This study has provided a global picture of the gene expression changes in a novel mutant with distinct color in the fruit pericarp of pummelo.
To test the efficacy of FAK inhibition in KRAS mutant NSCLC with distinct mutation cohorts (A: TP53, CDKN2A wild type, B: TP53 wild type, CDKN2A altered, C: TP53 mutant, CDKN2A wild type, and D: TP53 mutant, CDKN2A altered), a phase II multi-center study is currently underway in patients with KRAS mutant NSCLC who have already received one platinum doublet regimen.
In rare cases, both the original transposon insertions as well as the kanamycin resistance cassette can produce polar effects, resulting in mutants with phenotypes distinct from the null phenotype of the disrupted or replaced gene.
The analysis of mutants with a distinct phenotype that were generated, for example, by random mutagenesis, is a powerful approach to identify factors essential for biological processes.
These mutant arrays have been used to identify mutants with four distinct phenotypes (Table 2) as well as strains that are hyper-sensitive to cancer chemotherapeutics camptothecin and bleomycin (Hale and Runge, unpublished data).
