Sentence examples for mutants will need from inspiring English sources

The consequences of defective retrotranslocation or loss of the pre-emptive quality control pathway in these mutants will need to be examined more closely.

Poorly studied or recently isolated mutants will need to be genetically characterized, as the mapping strategy ultimately employed will depend on the nature of the mutation.

Fourth, in some homozygous mutants, maternal contribution of the gene products may compensate for their zygotic functions; therefore, embryos from homozygous mutant females will need to be examined to assess the function of these genes.

Thus, to achieve efficacy against V600EBRAF but avoid activation of wild-type BRAF in RAS mutant cells, the drugs will need to be exquisitely selective for the mutant protein.

The cause of the 10% penetrant Clr phenotype in ndk-1 single mutants and its enhancement by ksr-2 will need further investigation.

Further experiments with previous [70] and new inducible clock mutants will be needed to resolve these questions and to clarify the functional role of diurnal oscillations in metabolite and transcript levels in low temperature growth and freezing tolerance.

Genetic analysis of combinations of mutants will be needed to push the boundaries to define new gene and pathway interactions.

Future work using biogenesis mutants will be needed to clarify whether 22 nt LTR-associated sRNAs in Populus are more similar to the maize or the Arabidopsis genomes.

In addition to genetic screening for mutants that fail to perform mitophagy, future efforts will need to clarify the molecular signals for mitophagy.

Because of the redundancy of APP and APLP2, we will need to study agrin/APP/APLP2 triple mutant mice to properly evaluate the effect.

To test this speculation, we will need to collect data on mtDNA mutant loads for other rarer mtDNA mutations.