Sentence examples for mutants which would from inspiring English sources

We have developed a method of hotspot determination to uniquely validate the class of small RNA in the absence of readily available mutants, which would lend themselves to characterization of small RNAs.

In this case, polar growth would be expected to continue inappropriately in shs1-ps mutants, which would lead to growth of cells that are slightly elongated and abnormally large.

Given that we demonstrated M6A mutant to have increased nuclear localization, it will be of interest to specifically functionally interrogate the patient-derived KLF6 and KLF6-SV1 M6V mutants, which would both share the mutation, to better understand if their association with cancer arises from loss of the tumor suppressor or activation of the oncogenic variant.

Our results suggest increased activation of Rab7 disease mutants which would be predicted to correlate with alterations in the activity cycle.

N2 animals exhibited reduced Ca2+ responses in RMG compared to npr-1 mutants, which would be consistent with NPR-1 215V inhibiting RMG Ca2+ signaling.

To exclude preexisting mutants, which would bias the mutation frequency by so-called jackpots, a series of low-inoculum cultures is typically used (5 ).

This may be an indirect consequence of the base flipping defect in this mutant which would reduce the crucial interaction between the flipped base and the stacking tryptophan.

It would be wrong to conclude that only AKIN10 would phosphorylate the remaining three sites in this mutant, which would again complicate the interpretation of the results.

In contrast, neither the C124S mutant, which would be incapable of catalysing autodephosphorylation, nor the (C124S -4D C124S -4Dhich potentially mutant the phosphorylated state of PTEN, led to a decrease in spine density.

One way would be to use an analog-sensitive CDK1 mutant, which would obviate the need to guess how long CLN2 remains above the level required for Whi5 phosphorylation after the induction of CLN2 is terminated.

This unambiguity allowed us to draw conclusions about kinetoplast and nucleus number and structure in an example cell line, the SCC1-mutAB mutant, which would not be possible from a single DAPI micrograph.