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The article is then scanned for mutants, which in turn are linked to the relevant mutant records in GPCRDB.
Despite thorough screenings they could not obtain the desired type of mutants, which in their view suggested that the photoreceptor could be essential.
Database URL: http://www.MuteinDB.org One of nature's fundamental mechanisms to create genetic diversity in living organisms is the creation of mutants, which, in turn, leads to evolution.
For example, the root length of the axr2-1 pax1-1 double mutant is less than that of both the axr2-1 and pax1-1 single mutants, which in turn are both less than wild-type.
Although COH-3/4 associates with chromosomes of him-3 rec-8 animals, the intensity of COH-3/4 signal is less than that detected in him-3 single mutants, which, in turn, is less than that in wild-type animals (See also Figure 4 figure supplement 2 ).
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X-ray-structure-based rational design and the allocation of specific interaction residues by NMR-analysis led to the construction of Fd- and FNR-mutants, which in appropriate combination enabled an about 18-fold enhanced electron flow from Fd to HydA1 (in competition with equimolar amounts of FNR) in in vitro assays.
As we can see from the experimental results, this is clearly not the case in the PC-ΔPP2B mutant, which in fact may provide an interesting clue.
The design of the PIR reporter protein is based on a p53 R175H mutant which, in contrast to the short-lived, WT p53, has a significantly longer half-life (several hours), presumably due to its reduced susceptibility to proteasomal degradation [37].
Several transcripts encoding the enzymes involved in mETS were down-regulated in the fl mutant which in turn decreases the NAD+/NAD(P H ratio and efficiency of mitochondrial ATP production.
The difference between the two models is in the implementation of the clv1-1 mutant, which in each case is described by a single parameter - k3, weak for the loss-of-signal model and k8 for the interference model.
During the same time interval, Ca2+ efflux was observed in sos1 mutants, which resulted in a decrease in cytoplasmic Ca2+.
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