Sentence examples for mutants which do from inspiring English sources

Furthermore, interactions with ankyrin-B are required for InsP 3 R stability as abnormal InsP 3 R phenotypes, including mis-localization, and reduced half-life in ankyrin-B cardiomyocytes can be rescued by green fluorescent protein (GFP -220-kDa ankyrin-B but not by GFP -220-kDaankyrin-B mutants, which do not associate with InsP(3)R.

The development of ZFRs was only feasible following the isolation of 'activated' recombinase mutants which do not require any accessory factors, and recombine short dimer-binding sites [9] [12].

RNMT mutants which do not bind to RAM do not exhibit a localization defect [ 8].

To test this hypothesis, we used fog-2 (q71 ) mutants, which do not produce self-sperm and are essentially female (Schedl and Kimble 1988).

We did not take the final populations (years 900-1000), in order to exclude recent mutants which do not necessarily reflect selected genotypes.

This is in contrast to the clumped mitochondria in clu mutants, which do not show defects in fission and/or fusion, as viewed by transmission electron microscopy (TEM) and by analyzing Nebenkern development (Cox and Spradling, 2009).

The 12 mutants which transformed myeloid cells also trans-activated gene expression, whereas the 3 mutants which did not transform also did not trans-activate.

The M1 mutants, which did not co-immunoprecipitate with Hsp70, failed to induce apoptosis.

They also showed akin10 and akin11 single mutants, which did not have a striking phenotype.

This ambivalent picture is also reflected by our genetic interaction experiments between RSK and ERK mutants, which did not provide a conclusive answer about the relationship between RSK and ERK with respect to pre- and postsynaptic functions.

There was also a trend for decreased insulin sensitivity in df/df VFR compared with df/df-sham mutants which did not reach statistical significance (P = 0.0615) (Fig. 1D).