Your English writing platform
Discover LudwigSuggestions(5)
Exact(18)
Altered colony character or size might have imposed a growth disadvantage for two of the mutants, which could possibly account for apparently decreased invasion.
However a lower maximum growth rate was observed in 2L reactors as opposed to 24 deepwell plates for 9 out of 12 mutants which could be linked to the higher amount of dead cells in the benchtop bioreactors (12% vs. 2% in MTPs).
Interestingly, this configuration led us to measure a significant constitutive BRET signal between β-arrestin 1 and R137C or R137L mutants Figure 3b and c), but not with the wild-type V2 receptor (Figure 3a), indicating a basal recruitment of β-arrestin 1 by V2 mutants which could be associated with their constitutive activity.
We speculated that the increased residence time on Gab1 could prolong substrate turnover by the LS SHP2 mutants, which could compensate for their reduced phosphatase activity.
The migration of the Primordium is also slower in Amotl2a mutants, which could contribute to the deposition of the additional neuromast.
Generation and maintenance of continuous genetic variation may lead to partial protection and escape mutants, which could provide a "pump" that generates more variants and "new" viruses.
Similar(42)
Expression of these genes in relA/spoT mutant was significantly higher than in wild-type strain and rpoN mutant, which could suggest that this operon is regulated by the stringent response in negative manner.
The lower β(i), β(iii), β v) values are associated with the BEI and/or BEIIb mutant, which could imply that BEIIa is associated with β(ii), β vi) and β vi).
Currently there is no U1-70K mutant, which could be used for complementation with fluorescent protein tagged U1-70K fusion constructs.
On the other hand, we observed a low binding to DNA substrate in the case of the Y143R mutant which could be responsible for the catalytic defect in this enzyme.
The SPI-1 mutant lacking the entire SPI-1 coding region displayed lower levels of invasion compared to the invA T3SS mutant in both culture systems, and this could be a result of the absence of the entire SPI-1 PAI (Pathogenicity Island) in the SPI-1 mutant, which could potentially contain effectors aiding in bacterial invasion.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com