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We next investigated whether any of these pmt3 mutants were sensitive to HU or other toxins.
Previous studies reported that spb1DA mutants were sensitive to paromomycin, and that sparsomycin had no effect [19].
In total, 53 of the 73 EcoRIs non-RAD52 group mutants were sensitive to bleomycin (4 μg/ml) and 44 mutants were sensitive to MMS (2 mM).
We observed that buffy null mutants were sensitive to crowded vials or poor food quality.
However, eight A. fumigatus phosphatase null mutants were sensitive to GEL.
The eight RAD52 group mutants were sensitive to every clastogen tested, including bleomycin, MMS and gamma radiation.
Similar(41)
These results indicate that sod1Δ mutants are sensitive to even mild deficiency.
Strikingly, ccr4Δ and dhh1Δ mutants are sensitive to IR only as diploids and not as haploids, indicating that the radiation sensitive IR defect lies in G1 [39].
Surprisingly, the behaviours of ΔrecG ΔclpX and Δruv ΔclpX mutants were very different from each other despite both mutants being sensitive to 2-AP.
SUMO chain mutants are sensitive to the DNA synthesis inhibitor, hydroxyurea (HU), but not to other genotoxins, such as UV, MMS or CPT.
Recently, Schneider and colleagues showed that eiger mutants are sensitive to systemic infection by gram-positive cocci, a type of extracellular bacteria [17].
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