Sentence examples for mutants were combined from inspiring English sources

We also confirmed that these observed genetic interactions were not a consequence of recombinant suppression resulting from gene proximity because no noticeable effects on growth were observed when ΔrbbA or ΔyhjD donor mutants were combined with deletions of functionally unrelated genes flanking nuo, sdh and cyo operons.

Consistent with this, substitution of Phe54 at the tip of the HCDR2 loop of CR6261 with leucine or alanine reduced binding in relation to hydrophobicity, and additive decreases in binding were observed when CR6261 mutants and HA mutants were combined (Fig. 9b).

What if these mutants were combined with ATPase-defective mutations?

The alcohol dehydrogenase promoter and mixed acid fermentation mutants were combined to improve P3HB production under microaerobic condition.

When GTF alleles and Pol II mutants were combined, we observed allele-specific interactions between GTF alleles and Pol II GOF/LOF mutant classes.

Because we observed above that GTF TSS defective mutants and Pol II TSS defective mutants conferred enhanced growth defects when same-direction TSS shifting mutants were combined but showed mostly weak, conditional, or directional suppression when opposite direction shifting mutants were combined, we examined how each class of double mutant affected TSS distribution at ADH1.

However, a functional enzyme pair is reconstituted when both E2 and E3 mutants are combined.

Crossover defects and/or fused commissures are also common phenotypes observed when abl mutants are combined with mutations in a variety of genes implicated in the regulation of cytoskeletal dynamics (e.g. [38], [39], [44], [50], [51]).

For example, vegetative to reproductive transition defects are observed when blr mutants are combined with mutations in poundfoolish (pnf), the gene with which BLR shares most similarity in Arabidopsis[ 11], which are not observed in multiple knox1 mutants [ 12, 13].

A similar observation has been reported for another glycosylase, MYH, and only when the two mutants are combined or another stressor, such as UV exposure, is introduced is an increase in tumour incidence observed [ 55, 56].

For instance, the conspicuous loss of adaxial cell identity characteristic of yab triple or quadruple mutants is not seen in lines lacking co-repressor activity, nor when single or double yab mutants are combined with mutations in the LUG and LUH co-repressors [ 10, 23].