Sentence examples for mutants were caused from inspiring English sources

These results indicate that some ARM phenotypes in the β-catenin GOF mutants were caused by abnormal Bmp signaling.

Several mutants were isolated in both selections, however we were only able to confirm the gefE mutant through recapitulation experiments (i.e., the other mutants were caused by secondary mutations in addition to the identified REMI insertion).

To check whether the G1 mutants were caused by TALEN-B3 only or TALEN-B3 together with ssODN, 5 G1 mutants were allowed to develop to moths and subjected to genomic DNA extraction after mating.

To confirm that the upper bands of both WT and the two single mutants were caused by N-linked glycosylation, we used PNGase F to remove all N-glycans from TβRII.

To confirm that the phenotypes observed in cycd1 1 cycd3;3 mutants were caused by loss-of-function of these cyclins, we examined a second loss-of-function allele of CYCD1 1, cycd1 1-2, in combination with cycd3 3.

To determine whether the cardiovascular defects observed in the Wnt1cre; Ilk flox/flox mutants were caused by defective differentiation of NCCs into smooth muscle cells, we analyzed the expression of smooth muscle actin (αSMA), a broadly used marker of smooth muscle differentiation.

Here we show that the defects in sputnik mutants are caused by mutations in cadherin 23 (cdh23).

These findings indicate that the higher nitrate content in the nlp7 mutants is caused by the reduced nitrate assimilation, rather than altered nitrate uptake.

However, we cannot rule out the possibility that the leaf variegation in the z3 mutants is caused by the citrates by themselves.

Thus, we conclude that the low availability of asparagine in gs1 2 mutants was caused by the reduction in glutamine content, which is required for the up-regulation of OsAS1 expression.

Our results strongly support that familial FSGS associated with TRPC6 mutants are caused by podocyte dysfunction.