Sentence examples for mutants we noted from inspiring English sources
To design quadruple mutants, we noted that recent structural work reported a set of Ct-Doc domains that differ from the canonical duplicated Ser-Thr sequences.
During the process of generating stable cell lines for some Pen-2 mutants, we noted that all clones of I53A had Pen-2 expression markedly lower than that of wild-type lines.
In the exosome mutants, we noted that some ectopically expressed, meiosis-specific transcripts appeared to be smeary and larger than the natural transcripts produced during meiosis or those expressed in the mmi1-ts3 mutant.
When analysing phosphopeptides in the Ser358Ala and Ser343Ala mutants, we noted that Ser was not phosphorylated in the Ser343Ala mutant, a finding that was confirmed using anti-phosphoSer antibodies.
In the course of characterizing embryonic hemoglobin gene expression in rps19 mutants we noted that mRNA for hemoglobin beta e1 (hbbe1) was not reduced whereas hemoglobin gene hbbe3 mRNA was increased by >50-fold.
Indeed, when we made the N100W and N100Y mutants, we noted that PLP binding was altered, and both the binding constants (k m ) and catalytic activities (kcat) were lowered significantly compared to the wild type.
Although Pif1 clearly demonstrates a telomerase-independent effect in cdc13-1 mutants, we note that cdc13-1 tlcouldxo1Δ mutants could grow at 27°C, whereas cdc13-1 tlcouldif1Δ mutanot compareot (comparowsows 11 12 with 7 8, Figure 5A).
When performing experiments on measuring the growth and incorporation of 14C-acetate into irradiated and non-irradiated melanized C. neoformans cells and its non-melanized Lac mutant, we noted that non-irradiated Lac cells grew better and incorporated more 14C-acetate than non-irradiated melanized cells (Fig. 6b,d).
By sequencing p53γ cDNA in breast tumours expressing mutant p53, we noted that p53γ cDNA contained the same mutation as the p53 gene, indicating that p53γ was expressed by the tumour cells and not by cells from the stroma.
When analysing spore viability in homologous SGS1 mutant strains, we noted a significant increase in the number of two viable spore tetrads for sgs1Δ/sgs1Δ (27.08%) and for pCLB2-SGS1/sgs1Δ (19.1%) compared to wild type (0.9%).
During handling of Bace1−/− mutant mice, we noted that their movement was altered.
