Sentence examples for mutants we hypothesized from inspiring English sources
Because these cells are absent in merovingian mutants, we hypothesized that there would be a global acidification of the animal's internal environment.
Given the rapid rate of GDP dissociation in the Rab7 disease mutants, we hypothesized that nucleotide exchange might be misregulated and occur independent of GEF activity.
Thus, although major deficits in locomotion are not present in rpm-1 mutants, we hypothesized that synapse formation defects in these animals might lead to subtle effects on locomotion.
As increased stress responses and other transcriptional changes together stimulate longevity in insulin-like-signaling (ILS) mutants, we hypothesized that upregulation of stress responses as a result of ercc-1/xpf-1 deficiency might cause additive daf-2 life-span extension.
Because ERV14 deletion mutants have small, abnormal forespore membranes similar to erp2Δ and erp5Δ mutants, we hypothesized that, parallel to the S. cerevisiae ER cargo receptors, erp2+ and erp5+ might become essential for ER exit of integral membrane proteins in S. pombe sporulation.
Given that variability in alternative splicing or NMD could not explain the selective skeletal muscle disarray in ttnac/c mutants, we hypothesized that this variation in severity could be due to ttnac/c mutants interfering with the action of ttnb, although the ratio of mutant to wild-type transcript of ∼20% made this an unlikely scenario.
As observed in the cpr1 and bal mutants, we hypothesize that EMS treatment has destabilized the genome of svt2 by interrupting one or more mechanisms involved in genomic inheritance.
Based on abnormalities in MT dynamics in interphase cells in hoxb1b mutants, we hypothesize that Hoxb1b-dependent MT dynamics during oriented cell division may regulate neuroepithelial morphogenesis in the anterior hindbrain.
Based on the demonstrated decoupling of the hAID deamination activity on C and 5 mC, particularly evident for the N51A mutant, we hypothesized that significant differences in the molecular mechanisms involved in hAID's recognition of C- and 5 mC-containing substrates must exist.
Since the intracellular Ca2+ level could be increased by H2O2, especially in the tps1Δ mutant, we hypothesized that Ca2+ signaling might regulate C. albicans apoptosis, and the higher sensitivity of tps1Δ mutant to H2O2 might be due to its higher intracellular Ca2+ level.
As an alternative explanation for the attenuated phenotype of the mptC mutant, we hypothesized that the presence of monomannoside-capped LAM is detrimental for virulence in zebrafish embryos.
