Sentence examples for mutants we demonstrate from inspiring English sources
Using a panel of CIITA mutants, we demonstrate that cytoplasmic CIITA increases Gag-Pol polyprotein levels.
By using cysteine to alanine mutants, we demonstrate that ROS-mediated activation of RhoA is dependent on cysteines 16 and 20.
Using functional assays of bacterial adhesion and internalisation, microscopic analysis, and a panel of CEACAM1 deletion mutants we demonstrate that the engagement of CEACAM1 by non-opaque meningococci occurs in a manner distinct from Opa protein-mediated association.
By using different RTN1-C mutants, we demonstrate that the observed effects depend on RTN1-C N-terminal region and on the integrity of the microtubule network.
Using viral deletion mutants, we demonstrate that the expression of immediate early viral genes is critical for the suppression of the miR-199a/214 promoter.
Employing these mutants, we demonstrate that interaction of WNK isoforms is not essential for their T-loop phosphorylation and activation, at least for overexpressed WNK isoforms.
In a recent study carried out with alpha toxin and perfringolysin O mutants we demonstrated an essential role of both toxins in bovine enterotoxemia [ 8].
In our study using nearly 60 million mapped reads per condition to analyze 4295 mutants, we demonstrated that the quality of our dataset was maintained with approximately 10-fold fewereadsds.
Furthermore, we have previously shown that PIN protein abundance is not altered in the d6pk mutants: We demonstrated that the loss of D6PK genes in the d6pk012 triple mutant does not alter the abundance or localization of the PINs PIN1, PIN2, and PIN4 abundance (Zourelidou et al., 2009).
By using an atrbohD/F double mutant we demonstrate here that dark-induced H2O2 formation occurs by a similar mechanism in Arabidopsis.
Using the glycolate-accumulating ΔglcD1 mutant, we demonstrate enhanced 13C partitioning into the glycolate pool under conditions favouring photorespiration and enhanced 13C partitioning into the glycine pool of the glycine-accumulating ΔgcvT mutant.
