Sentence examples for mutants we chose from inspiring English sources

From a screen for potential gametophytic mutants, we chose the Arabidopsis At3g58170 and At4g14455 loci (BET11 and BET12) for study (Additional file 1: Table S1).

To directly test apathy in these mutants, we chose a task that has minimal physical requirements.

Given the severity and 100% penetrance of the gland phenotype in these mutants, we chose to examine iv38 in more detail.

Given the absence of any overt developmental defects in sigmar S mutants, we chose to further utilize this tissue to investigate the potential functional roles of Sigmar during development in vivo.

To quantitatively evaluate and compare the rates of generating genomic DNA mutations (termed as mutation rates for short) by different dnaQ mutants, we chose the widely used rifamycin resistant colony generation frequency as an indirect indicator [ 21- 23].

Since we were not confident that the time investment would yield new information (given that this mutation is already encompassed in the Lis15A quintuple mutant), we chose to invest our time in experiments that would test the major mechanistic hypothesis of the paper, as suggested in general point #1 (even if those experiments were unsuccessful in the end).

Hypoxia N2 +  hif-1 : For the hypoxia-treated samples including the hif-1 mutant, we chose mir-58-3p as highly expressed (375488,779 reads), mir-230-3p as intermediately expressed (2681,376 reads) and mir-357-3p mir-357-3p mir-357-3p287,386 reass) to valowlyexpressed.

To determine whether inhibition of casein kinase I and cdk5 activities would display beneficial effects in decreasing the aggregative properties of pathogenic parkin-mutant protein, we chose to analyze three distinct point mutants whose pathogenic mechanism of action seems to involve enhanced aggregation (14– 14).

Because the low penetrance of obtaining phenotypically mutant Vangl1gt/gt homozygous embryos precluded analysis of mutant nodes, we chose to examine the role of PCP signaling in embryo lateralization in the homologous structure in Xenopus, the gastrocoel roof plate (GRP) [8] [10].

Based on 5A mutant phenotypes, we chose three categories to construct sub-networks of "direct interactions" among differentially regulated genes; (i) chromosome segregation, (ii) cell wall and membrane biosynthesis, (iii) cell cycle regulation and DNA repair (Fig. 3).

To test whether increased PM localization is a factor in the higher activity of oncogenic mutant PI3Kα, we chose to take advantage of our ability to express and purify the recombinant p110α/p85α heterodimer in such a way that the ratio of subunits is 1 1 [ 30].