Sentence examples for mutants we assumed from inspiring English sources
Because we could not see a major change of BicD protein content in any of the Ser mutants, we assumed that reduced hyperphosphorylation of BicD leads to a higher level of the hypophosphorylated isoform, rather than to degradation.
Given the strong overlap in gene expression changes between and consistent phenotypic alterations of all three mutants we assumed that plasmid loss has no great impact on the experimental results regarding the ∆ctrA mutant.
For the I93M mutation we assumed that either the mutant had lower hydrolase activity than wild-type or that in addition the I93M mutant had a greater propensity to be damaged.
To parameterize the 'deleterious mutant' scenario, we assumed that the in vitro fitness cost manifested itself through a reduction in the within-host viral production rate.
Because of the low density of mutations expected in mutants isolated from mutagenesis screens, we assumed only one causal mutation influenced the phenotype of interest in each mutant.
We assumed that mutants with enhanced glycerol utilization capability would grow faster than most other colonies in the background.
Since no mutants were observed until after the second time point, we assumed that the mutant arose only thereafter and used an informative prior with a point mass at zero for the population mutant frequency at generation 25.
We assumed that all mutants have unchanged quantum yields, which was justified by the localization of the mutations that are far from the residues involved in FMN binding.
We assumed that each mutant could revert to wild-type with the same probability.
In the current study, we assumed that if a mutant protein was involved in carcinogenesis or tumor progression, this mutant would be expressed and therefore detectable in tumor mRNA.
To facilitate this undertaking we assumed that specific CM mutants could be categorized as Ca2+ activating (thin filament activator) or Ca2+deactivating (thin filament deactivator) archetypes.
