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Interestingly, the ability of SAC components to suppress APC/C mutants was rather allele-specific.

Instead, the reduction in lignin levels in the c4h, 4cl1, ccoaomt1, and ccr1 mutants was rather associated with an increase in matrix polysaccharide levels, according to the weight loss after a TFA extraction.

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An alteration in strand bias of viral small RNAs in rdr mutants is rather puzzling, since the assumed function of a host RDR protein is to synthesize dsRNA from ssRNA templates.

Although this insertional screening was carried out on a large scale aimed at identifying genes essential for early development, the phenotypic descriptions of these insertional mutants were rather preliminary and most of the images provided were taken at 2 to 4 dpf.

However, we consider it unlikely that all mRNAs found enriched in the eIF3e complex are exclusive translational targets of this complex, because the cellular phenotypes of eif3e mutants are rather discrete.

It is worth noting that the SOS constitutive phenotype of ε knockout mutants is rather modest (dinD:: lacZ expression increased by only approximately 50%; see Table 3), precluding strong conclusions based on intermediate levels of basal SOS expression.

Therefore, we can assume that selective constraints in tRNAs are most likely influenced by Ne and that this effect is strong if selection is weak, whereas in the case of strong selection, our observations follow theoretical predictions, which show that the fixation time of compensatory double mutants is rather independent of Ne (eq. 8c in Stephan 1996).

However, it is unlikely that the restoration of Cbl binding in the Y1045+ mutant caused the partial rescue of CME through EGFR ubiquitination, since the EGF dose response of CME of this mutant was rather different from that of its ubiquitination, while the dose response of its NCE was congruent with it (Supplementary Figure 12B).

The strain lineage of the D15 mutant is rather complex, therefore, we used a bulk segregant approach, which narrows down the genomic region responsible for the phenotype.

Thus the LVV residues of the heptad repeat motif, like the residues exchanged in the D5ALAc mutant, are rather functionally irrelevant.

Considering the plantation methodology adopted, germination frequency, and fibre yield per plant, it is expected that fibre yield will be about 3.18 ton/hectare in control and 2.76 ton/hectare in mutant but such variation is rather compensating due to significantly higher seed yield in mutant than control.

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