Sentence examples for mutants under starvation from inspiring English sources

However, atg32Δ cells showed nearly normal respiratory activity (Figure 2C), indicating that selective mitochondria elimination is not responsible for the observed respiratory defects caused in atg mutants under starvation conditions.

Whereas expressing Slif anti in PTEN clones resulted in a slight reduction of the mutant tissue under normal conditions, it caused a nearly complete elimination of the PTEN mutant tissue under starvation conditions, while not affecting the control clones.

Removal of FoxO slightly suppresses the overgrowth phenotype of PTEN mutant tissue under starvation.

10.7554/eLife.00380.041 Figure 8. Model of hyperplastic overgrowth of PTEN mutant tissue under starvation.

Surprisingly, PKB levels are strongly reduced in the PTEN mutant tissue under starvation.

(C Wingsgs of flies with PTEN mutant heads under starvation are smaller than wings of control flies.

Food switch experiments reveal that a short starvation period early after clone induction is sufficient to result in the overgrowth phenotype of PTEN mutant tissue under starvation.

(A ) Restoring insulin signaling by means of Dilp-2 expression (driven by ey-Gal4 ) suppresses the overgrowth of PTEN mutant cells under starvation.

Therefore, low levels of circulating DILPs are sufficient to boost PIP3 levels and PKB activity in PTEN mutant cells under starvation.

The heterodimeric G-protein complex Gtr1-Gtr2, the yeast ortholog of mammalian RRAGA/B-RRAGC/D, is an upstream regulator of TORC1.,, Therefore, we assessed the potential relationships between Gtr1-Gtr2 aNpr2-Npr3pr3 by examining double-deletion mutants under nitrogen-starvation conditions.

Since endogenous and overexpressed wt ZBTB16 proteins are degraded upon serum starvation while S184A/T282A mutant is not, this experiment provides an opportunity to test if the persistent levels of S184A/T282A mutant under serum starvation condition might be able to suppress the increases in Atg14L and autophagy.