Sentence examples for mutants to those from inspiring English sources

Comparison of the new mutants to those obtained previously reveals distinctly different subsets of enzyme active-site mutations with either improved overall enzyme activity, or improved specificity towards either the C2-hydroxylated or non-natural aliphatic aldehyde substrate.

Although it is not straightforward to homologize lobules in lissencephalic mutants to those in wild type, the reduction in lobule length appears to involve all lobules except lobule X.

Ratios of Ka (1/ Kd) values of congerins and their mutants to those of Con-anc and ConI were calculated.

These procedures may bias the range of potential Con- mutants to those with membrane alterations, leaving out genes involved in other functions (e.g. DNA processing reactions).

In comparing the kinetic constants of our mutants to those of wild-type AANATA (Table 4), we find that three of our mutants stand out: E47A, P48A, and R153A.

Interestingly, in cases where the human fibroblast lines allow an assessment of survival for a specific allele (R683W, R112H, R722W and possibly R601L, see below), similar UV sensitivities have been reported for XP and TTD mutants to those we see here (5× 12× elevated; Lehmann et al., 1988; Ichihashi et al., 1988; Broughton et al., 1994; Takayama et al., 1995; Takayama et al., 1996).

Regardless of the experimental technology used, the screening strategies aim to quantify the extent to which a mutation in one gene modulates the phenotype (or fitness) associated with altering the second gene, either by explicitly measuring or analytically comparing the observed fitness of double-mutants to those of single-mutants.

Inhibition of either degradation pathway fully restored SCARB1 protein levels of the mutant to those of wildtype levels (Figure 8).

Inhibition of either degradation pathway fully restored SCARB1 protein levels of the mutant to those of wildtype levels indicating that the1179N mutant protein is misfolded and degraded.

Based on this notion, the importance of Y. pestis Hfq under stress conditions was examined by comparing the growth or survival characteristics of the Δhfq::KmR mutant to those of the wild-type strain.

To gain insight into the crucial role of Phe429 in P450 catalysis, we have compared the characteristics of the P450 F429H mutant to those of other mutant and wild type P450s lacking the conserved phenylalanine.