Sentence examples for mutants to interact from inspiring English sources

The activity of hPXR mutants on CYP3A4 expression correlates with the ability of hPXR mutants to interact with co-activator SRC-1.

B Western blot analysis demonstrating the ability of different PICH mutants to interact with endogenous Plk1.

This result suggests that the absence of regulation by partially liganded CaM was due to the inability of the CaM mutants to interact with the CaMBD of AC1.

We first used size-exclusion chromatography to test the ability of the Lis1 mutants to interact with a functional dimerized dynein construct (GST-dynein331kDa) (Reck-Peterson et al., 2006).

Our findings demonstrate that missense mutations in MUSK can result in a severe form of CMS and indicate that the inability of MuSK mutants to interact with Dok-7, but not with Lrp4 or Tid1, is a major determinant of the pathogenesis of the CMS caused by MUSK mutations.

The failure of the RING domain mutants to interact with Mei-P22 is not due to altered protein expression levels or degradation, as we do not observe any obvious differences in the amount or size of the RING domain mutant proteins compared to wild type.

The much reduced ability of L157A mutant to interact with Rab8 (Fig. 7B) and TfR (Fig. 7C) suggests that the optineurin association with Rab8 and TfR requires, at least in part, an intact leucine zipper motif.

We first examined the ability of each Noxa mutant to interact with MCL-1 by co-immunoprecipitation.

This demonstrated that the ability of the mutant to interact with MRAP is unaffected by the substitution of the tyrosine residue.

This behavior of Bub3R217A R239A-mCherry agrees with the inaBub3R217A R239A-mCherrynt Bub3 mutagrees interact with phosphorylathe MELT repeats inability

It should nonetheless be noted that the Co-IP results presented in Figure  6 show that removal of this region does not completely abolish the ability of the mutant to interact with endogenous TDP-43.