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We used these mutants to identify functional genes that are potentially responsible for adhesion or invasion.
In this strategy we used the correspondence of warnings and mutants to identify bug kinds more probable to produce true positive warnings.
Mutation-based fault localization (MBFL) is a recently proposed fault localization approach via mutation analysis, which uses the location of mutants to identify the faulty statements.
Since few mycobacterial proteins have so far been directly implicated in the interactions between M. tuberculosis and host cell apoptosis, we screened M. tuberculosis H37Rv transposon mutants to identify mutants that fail to inhibit cell death (FID).
Subsequently, the enrichment patterns were compared among the mutants to identify the conservation of functional groups among the mutants.
In this report we screened both ionizing radiation (IR) sensitive mutants and an unselected pool of yeast deletion mutants to identify additional suppressors of GAL-induced BRCA1 lethality.
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We carried out microarray analysis of a sphinx mutant to identify possible pathways in which sphinx might be involved.
It was necessary to use a spore-colour mutant to identify a cleistothecium produced by crossing the two strains; A. nidulans is homothallic, and genetically distinct strains are much more likely to self than to cross fertilize [62], [63].
Therefore, it is necessary to screen seeds harvested from each putative mutant to identify the relatively small percentage that exhibit a heritable sis phenotype.
In this work, we have used reactivation of the NMD pathway in an NMD-defective Drosophila mutant to identify directly targeted genes.
They then genetically disabled the candidate pathway and compared the suites of small molecules, the metabolomes, of wild type and mutant to identify a molecule present in wild type but absent in the mutant.
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