30– 33 Several groups have employed B cell line transfectants expressing Y→F mutant FCRLs to help define their cytoplasmic effector recruitment associations in the context of BCR ligation.
In contrast, the S. lacuscaerulensis catalase mutant was unable to help Prochlorococcus in liquid, but by an unknown mechanism actually raised HOOH levels in culture media relative to sterile controls (Table S2).
We conclude that Gp39.2 directly or indirectly enables the mutant GroEL44 chaperone to help UmuC reach its native active state.
Such an approach could be extended to identify other specific interactions between ribosomal protein mutants and snoRNA deletions to help understand the role of rRNA modifications, which are still largely unknown.
Professor X (James McAvoy) is still involved with his School for Gifted Students, trying to help young mutants adjust to society, while other, old-school mutants are having a tougher time.
Agreeing to help release mutants that Stryker has captured, Gambit takes Logan to Stryker's facility on Three Mile Island.
A diverse set of publicly available mutants is needed in wheat to help assign function to its genes including potential candidates of agronomic importance.
The development of high-throughput phenotyping pipelines for these and other large-scale projects allows investigators to search and integrate large amounts of directly comparable phenotype data from many mutants, on a genomic scale, to help develop and test new hypotheses about the origins of disease and the normal functions of genes in the organism.
Additional tools to help associate mutant phenotypes with specific genetic loci, including chromosome duplications and deficiencies, are also available.
Recently, knock-in animal models expressing physiological quantities of mutant APP have been generated to help differentiate between synaptic and cognitive effects caused by overexpression and those by mutation of APP.
