Sentence examples for mutants to demonstrate from inspiring English sources
However, studies by Liu et al. [15, 16] utilized knock-down and loss-of-function dcl1 and dcl4 RNAi mutants to demonstrate a role for OsDCL1 and OsDCL4 in small RNA biogenesis and plant development.
Here, we use Walker A and B mutants to demonstrate that D1 is capable of hydrolyzing ATP and show for the first time that nucleotide binding in the D2 domain increases the catalytic efficiency (kcat/Km) of D1 ATP hydrolysis 280-fold, by increasing kcat 7-fold and decreasing Km about 40-fold.
We used deletion mutants to demonstrate specificity of the assay, and we used optimized conditions to assay insulin-like gene expression throughout the C. elegans life cycle.
These results were extended using fluorescence recording from the L520C C445V C449V and the inactivation-removed S620T E519C C445V C449V mutants, to demonstrate that hERG channel activation is accompanied by a rapid displacement of S4 detectable at E519C as a rapid voltage-dependent fluorescence quenching that precedes pore opening.
We use mouse mutants to demonstrate that in the absence of Bace1, muscle spindle numbers are reduced and spindle maturation is impaired.
As a key argument, the authors use the akin10 GABI_579E09 T-DNA insertion mutant to demonstrate that AKIN10 is indeed responsible for in vivo phosphorylation of bZIP63.
Most previous studies used Aurora-C KD mutant to demonstrate the roles of Aurora-C in cancer cells and suggest that Aurora-C in somatic cancer cells has functions similar to those of Aurora-B.
While F637S showed clean single-step unfolding, both WT and the remaining mutants appeared to demonstrate more complex unfolding.
We used single mutants of either outC, or hrcV and a double mutant outC/hrcV to demonstrate that DspA/E from 3937 is delivered into the plant cytosol in a T3SS-dependent manner.
We took advantage of the phylogenetic conservation of both gene and mutant residue, to demonstrate the pathogenic role of the human variant in a yeast recombinant model carrying the equivalent mutant allele.
Here we use the PBS escape mutant B2 to demonstrate the capacity of the synthetic tRNAB2 to function in reverse transcription in competition with endogenous tRNAs in fibroblasts and embryonic carcinoma (EC) cells.
