Sentence examples for mutants to define from inspiring English sources

We performed a systematic analysis of 3,030 C. albicans mutants to define circuitry governing cellular responses to echinocandins.

We next made use of a panel of characterized Nef mutants to define the determinants that govern its effects on subcellular Lck distribution (Fig. 3).

We created a series of SU mutants by site-directed mutagenesis to introduce amino acid substitutions in the N44 region, together with a panel of V3-specific antibodies and then used these mutants to define residues critical for CXCR4 interaction.

Therefore, we used lacZ expression from the linc Brn1b locus in heterozygote mutants to define its expression in vivo.

Our work has included the preparation and investigation of site-directed mutants to define which protein side chains are involved in dimerization.

We analyzed multiple rad2 C-terminal deletion (rad2CΔ) mutants to define the sequences responsible for the CS-like phenotypes and examine the roles of those sequences in various cellular mechanisms.

The animal model allowed to identify active drugs, to assess the effectiveness of drug combinations, to demonstrate the prevention of the selection of resistant mutants and to define the duration of the treatments.

Next, we utilized defined mutants to determine whether members of the M protein family are involved in adhesion to hexadecane (Table 1, Fig. 4&5).

We selected a putative cyclohexanone receptor to demonstrate the feasibility of using C. elegans mutant lines to define a receptor's cellular and molecular characteristics.

We have employed experimental and computational analyses of Crx, Nrl, and Nr2e3 mutant retinas to define a comprehensive model of the mouse photoreceptor TRN which contains over 600 genes.

By analyzing the location of insertions using massively-parallel sequencing technology we used this mutant library to define genes essential for P. gingivalis survival under in vitro conditions.