Exact(3)
For four mutants, the model predicted the correct phenotypes very well.
Of the experimentally determined attenuated mutants, the model predicted that mutants defective in aromatic amino acid biosynthesis are avirulent (aroABCD).
Compared to other immunodeficient mutants, the model supports enhanced engraftment of allogeneic and xenogeneic cells, tissues, and tumors, as well as reconstitution of the hematopoietic system after bone marrow transplantation (23).
Similar(57)
Using desensitization analysis and knock out mutant, the model of different AtGLR subtypes was proposed (Stephens et al. 2008).
Accordingly, the evening feedback loop between TOC1 and Y was required to sustain short-period rhythms in the model in a simulated lhy, cca1 double null mutant: the model is relatively robust to the abolition of LHY/CCA1 function.
Also in line with observations for the Stm6 mutant, the model predicted increased linear electron flow and reduced mitochondrial TCA cycle activity (Table 5).
The positions of the characterized resistance mutants in the model structure identify two promising regions for the design of fusion inhibitors.
With the complete GRN model we can investigate the various mutants that the model can predict.
(A ) The positions of the four polymerization mutants in the model of the linker linker filament assembly interface.
Thus, mutants of the model are also unlikely to hold the property, as shown in Table 6.
Mutants of the model plant Arabidopsis thaliana have been used for studying SA-dependent regulation of plant defense responses.
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