Sentence examples for mutants the effect from inspiring English sources

Similar to caf1 and ccr4 mutants, the effect was also highly specific, and transposons, centromeres and HOODs were not affected (Additional file 1: Tables S6, S8 S9).

In this first high-throughput study of screening genome-wide heterozygous yeast mutants, the effect of using fermentable or non-fermentable carbon sources in the fermentation medium was investigated by growing the mutants in competition pools.

For combined Isl2-EphA3 ki/+ EphA5 mutants, the effect was similar, with the homozygous knock-out of EphA5 moving the collapse point further temporally than the heterozygous knock-out.

Concerning the isolation of Chlamydomonas lipid mutants, the effect of salt addition provides a convenient alternative to N-depletion procedures for inducing oil accumulation in mutant screens, which are often performed in microplates.

DOI: http://dx.doi.org/10.7554/eLife.09391.018 In experiments designed to measure rate constants for RNA dissociation from the K270A and K270R mutants, the effect of ATP was also similar to that observed for ATPγS (Author response image 2).

For the EmrE mutants, changing the loop length leads to relatively small shifts in the EOT ensemble; however, for the CB mutants, the effect of loop length on the EOT ensemble is much larger, with the new short-loop CB mutant exhibiting a much weaker bias towards the Ncyto/Ccyto topology in the EOT ensemble.

Our genetic data show that although mutations in the SWR1 complex components PIE1 and SEF are epistatic on brm mutants, the effects on FLC expression of an impaired SWR1 complex are overcome by brm mutations (Figure 6).

In hypomorphic Brca1 mutants, the effects of a Trp53-null or Trp53-heterozygous background were more pronounced, leading to a survival of Brca1 and Trp53 compound mutant mice to adulthood (Cressman et al, 1999; Xu et al, 2001).

However, in the W6A mutant, the effect is more drastic.

I25W mutant: The effect of mutation Ile25 to a larger residue such as tryptophan had previously been expected to restrict ligand docking in the Xe4 cavity.

Although loss of GUN4 caused a perturbation in Chl biosynthesis in gun4-II mutant, the effect is not as dramatic as it is in Arabidopsis, where the loss of GUN4 results in a nearly albino mutant.