Sentence examples for mutants the defect from inspiring English sources

In these mutants, the defect in basal ganglia probably gives rise to the misrouted CT axons.

In Δmpg1 mutants, the defect in appressorium formation can be restored by adding exogenous cAMP, suggesting that Mpg1 functions upstream of cAMP signal for appressorium formation [55].

Moreover, conditional inactivation of Mib1 in hematopoietic system also exhibited the characteristic phenotype of Dll1 mutants, the defect in the formation of marginal zone B cells (Song et al., our unpublished observation).

Together, these data suggest that in both human MADD cells and xav mutants, the defect in fatty acid oxidation compromises oxidative phosphorylation, leading to an upregulation in aerobic glycolysis as an alternative energy source, possibly as a consequence of AMPK activation, in an attempt to compensate for this metabolic insuffiency.

For these mutants the defects were similar in strength to the Dfs, with abnormal PGCs in well over half of the embryos from heterozygous mothers.

However, it is unknown if etioplast development is normal in sco1-1 mutantso so the defect could occur before or during seed maturation.

Strikingly, the re-expression of the WT and C/S mutant rescued the defect equally well.

Since Baz is essential for proper targeting of Crb and AJ [6], [7], mispositioned Baz in cnn mutants causes the defects of Crb and AJ (Figure 4B).

Both the S5A and the set1 deletion mutants fully suppressed the defect resulting from the lack of S2P.

Grossly normal somite morphology and patterning in mutants suggests that the defect is not in the specification of muscle precursors.

It is conceivable that the mutant plants sense the defect in the translation apparatus, for example defective ribosomes lacking RPL24.